Comparison of effect of High Intensity Exercise with Aerobic exercise on Nerve conduction velocity in Prediabetes
- Conditions
- Health Condition 1: null- Prediabetes
- Registration Number
- CTRI/2012/09/002975
- Lead Sponsor
- Government Medical College Aurangabad
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 44
1) Prediabetes: Impaired fasting glucose (IFG) - FPG 100-125 mg/dl OR Impaired glucose tolerance((IGT)- 2hr PPG 140-199mg/dl
2) Age group: 25 to 40 years.
3) Asymptomatic males with a normal baseline ECG
1.Resting blood pressure greater than or equal to 160/100 mm Hg
2. Triglycerides greater than or equal to 500 mg/dL
3. Factors that may limit adherence to intervention or affect conduct of the trial such as lack of time, amount of travel, and/or work or family stressors
4. Unable or willing to communicate with staff, to provide written informed consent, or accept the randomized assignment
5. Failure to complete behavioral run-in and baseline testing
6. Not physically capable of performing the exercise required of the study protocols
7. Plans to be away >4 weeks in the next 6 months
8. Lack of support from primary health care provider or family members
9. Significant weight loss in the past year ( >20 kg) or current use of weight loss medications
10. Current diagnosis of schizophrenia, or other psychotic disorders, or bipolar disorder
11. History of bariatric surgery within last 3 years
12. Other temporary intervening event, such as sick spouse, bereavement, or recent move
13. Other medical, psychiatric, or behavioral limitations that in the view of the principal investigator may interfere with study participation or the ability to follow the intervention protocol
14. Underlying diseases or conditions likely to limit lifespan and/or affect the safety of the intervention
15. Self-report HIV or tuberculosis
16. History or evidence of serious arrhythmias, cardiomyopathy, congestive heart failure, aortic aneurysm, or heart transplantation
17. Renal disease: currently receiving dialysis
18. Type I diabetes mellitus
19. Type 2 diabetes mellitus, defined as: Fasting plasma glucose levels greater than or equal to 126 mg/dL 2-hour postprandial Oral Glucose Tolerance Test results greater than or equal to 200 mg/dL
20. Any other medical condition or disease that is life threatening or that can interfere with or be aggravated by exercise
21. Chronic obstructive lung disease, peripheral vascular disease or angina that limits ability to follow exercise protocol
22. Advanced neuropathy or retinopathy
23. Consuming alcoholic beverages, Smoker or have used nicotine/tobacco products within the last 12 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method erve Conduction VelocityTimepoint: 6 weeks
- Secondary Outcome Measures
Name Time Method Audiovisual reaction timeTimepoint: 6 weeks