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Clinical Trials/NCT01595815
NCT01595815
Completed
Not Applicable

Successful Pregnancy and Delivery After AOA in Couples With Repeated Complete Fertilization Failure or Low Fertilization Rates

Maria Fertility Hospital1 site in 1 country100 target enrollmentMay 2007
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ConditionsInfertility

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Infertility
Sponsor
Maria Fertility Hospital
Enrollment
100
Locations
1
Primary Endpoint
Fertilization rate
Status
Completed
Last Updated
11 months ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

Artificial oocyte activation with strontium chloride or calcium ionophore improves fertilization, embryo quality, pregnancy and delivery rate in women who showed complete fertilization failure or low fertilization rates

Registry
clinicaltrials.gov
Start Date
May 2007
End Date
April 2014
Last Updated
11 months ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Jun-Woo Kim, Principal Investigator

Maria Fertility Hospital

Maria Fertility Hospital

Eligibility Criteria

Inclusion Criteria

  • •Fertilization rate was less than 30% after conventional ICSI.
  • •Fertilization rate was less than 50% after ICSI with calcium ionophore.
  • •Repeated complete fertilization failure or low fertilization rates following ICSI in previous cycles

Exclusion Criteria

  • •Fertilization rate was more than 30% after conventional ICSI
  • •Fertilization rate was more than 50% after ICSI with calcium ionophore.
  • •Successful pregnancy and delivery after ICSI in previous cycles

Outcomes

Primary Outcomes

Fertilization rate

Time Frame: 18 hours

Secondary Outcomes

  • Embryo quality(3 Days)
  • Pregnancy and Implantation rates(2 months)
  • Assessment of Infant health care(birth and at 3, 6, 12, 24, 36, 60, and 72 months)

Study Sites (1)

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