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Phase I/II trial of percutaneous vertebroplasty combined with radiotherapy for vertebral metastasis

Phase 1
Recruiting
Conditions
vertebral metastasis
Registration Number
JPRN-UMIN000031321
Lead Sponsor
Kobe University Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
36
Inclusion Criteria

Not provided

Exclusion Criteria

1)Patients can not maintain the position needed for treatment 2)Target lesions is cervical vertebrae or sacrum 3)The number of terget lesions was more than 4. 4)Bilsky Grade >= 1c 5)History of radiation therapy or surgery for target lesions 6)Bleeding tendency (Platelet counts <= 50,000 or PT-INR > 1.5) 7)Spondylitis or discitis 8)History of major drug allergy

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To evaluate short-time safety of percutaneous vertebroplasty combined with radiation therapy for vertebral metastasis with symptomatic skeletal events
Secondary Outcome Measures
NameTimeMethod
To evaluate safety and efficacy of percutaneous vertebroplasty combined with radiation therapy for vertebral metastasis with symptomatic skeletal events
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