NCT02577679Unknown不适用
Associations Between Periodontitis and Autoimmune Antibodies in Rheumatoid Arthritis Disease
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 47
- 试验地点
- 1
- 主要终点
- Periodontal pocket depth and clinical attachment level
研究概览
简要总结
The aim of this case control study is to explore the possible association between periodontal destruction and serum anti-CCP antibodies in RA patients and healthy subjects.
详细描述
In patients with RA, the anti-CCP antibody titer seems positively correlated to their periodontal destruction and disease activity in comparison with healthy subjects.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Periodontal pocket depth and clinical attachment level
时间窗: Baseline
Lower then 4 millimeter: normal Higher then 4 millimeter: diseased/previously diseased
Serum level of anti-cyclic citrullinated peptide/protein antibody
时间窗: Base line
Lower then 7 Unit/milliliter: negative 7-10 Unit/milliliter: weak positive Higher then 10 Unit/milliliter: positive
次要结局
- Serum level of tumor necrotic factor alpha(Baseline)
- Serum level of interleukin 6(Baseline)
- Serum level of interleukin 17(Baseline)
- Serum level of anti-mutated citrullinated vimentin(Baseline)
研究者
研究点 (1)
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