EUCTR2019-002239-27-ES进行中(未招募)1 期
Study on the relationship between periodontal disease and serum levels of ultrasensitive Reactive C-Protein and fibrinogen - PERIODONTITIS AND INFLAMMATORY MARKERS
Clinica Dental AndreuDental0 个研究点目标入组 123 人开始时间: 2019年7月26日最近更新:
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中(未招募)
- 发起方
- 入组人数
- 123
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
入选标准
- •Patients with a Probing Depth > 3 mm in at least oneprobing site in two or more teeth
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 60
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 63
排除标准
- •Patients who have total edentulism, have received periodontal treatment in the last year, there being a decrease in inflammatory activity, are pregnant or breastfeeding, given the
- •immunological tolerance during pregnancy, they are diagnosed of ulceronecrotizing gingivitis (NUG), being an acute process,
- •ulceronecrotizing periodontitis (NUP), being an acute process or diagnosed with HIV, due to the state of immunosuppression, recent
- •history of angina, myocardial infarction or CVA, since they suppose a confusion factor when elevating the serum levels of the biomarkers,
- •antecedents of acute inflammatory processes or recent traumatisms, suffer chronic ingestion of non-steroidal anti-inflammatory drugs
- •(NSAIDs) or glucocorticoids, decrease the immune and inflammatory response, have taken antibiotics in the last three months, since they decrease the inflammatory activity and therefore the serum levels of
- •biomarkers.
研究者
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