RELATIONSHIP BETWEEN PERIODONTITIS AND INFLAMMATORY MARKERS
- Conditions
- Patients with a diagnosis of periodontitis: There is interdental LCI in two or more non-adjacent teeth, or two or more teeth have a vestibular LCI = 3 with a PD > 3 mmTherapeutic area: Diseases [C] - Mouth and tooth diseases [C07]
- Registration Number
- EUCTR2019-002239-27-ES
- Lead Sponsor
- Clinica Dental AndreuDental
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- Not specified
- Target Recruitment
- 123
Patients with a Probing Depth > 3 mm in at least oneprobing site in two or more teeth
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 60
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 63
Patients who have total edentulism, have received periodontal treatment in the last year, there being a decrease in inflammatory activity, are pregnant or breastfeeding, given the
immunological tolerance during pregnancy, they are diagnosed of ulceronecrotizing gingivitis (NUG), being an acute process,
ulceronecrotizing periodontitis (NUP), being an acute process or diagnosed with HIV, due to the state of immunosuppression, recent
history of angina, myocardial infarction or CVA, since they suppose a confusion factor when elevating the serum levels of the biomarkers,
antecedents of acute inflammatory processes or recent traumatisms, suffer chronic ingestion of non-steroidal anti-inflammatory drugs
(NSAIDs) or glucocorticoids, decrease the immune and inflammatory response, have taken antibiotics in the last three months, since they decrease the inflammatory activity and therefore the serum levels of
biomarkers.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method