跳至主要内容
临床试验/EUCTR2019-002239-27-ES
EUCTR2019-002239-27-ES进行中(未招募)1 期

Study on the relationship between periodontal disease and serum levels of ultrasensitive Reactive C-Protein and fibrinogen - PERIODONTITIS AND INFLAMMATORY MARKERS

Clinica Dental AndreuDental0 个研究点目标入组 123 人开始时间: 2019年7月26日最近更新:
适应症
相关药物

试验速览

阶段
1 期
状态
进行中(未招募)
发起方
入组人数
123

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

入选标准

  • Patients with a Probing Depth > 3 mm in at least oneprobing site in two or more teeth
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range 60
  • F.1.3 Elderly (>=65 years) yes
  • F.1.3.1 Number of subjects for this age range 63

排除标准

  • Patients who have total edentulism, have received periodontal treatment in the last year, there being a decrease in inflammatory activity, are pregnant or breastfeeding, given the
  • immunological tolerance during pregnancy, they are diagnosed of ulceronecrotizing gingivitis (NUG), being an acute process,
  • ulceronecrotizing periodontitis (NUP), being an acute process or diagnosed with HIV, due to the state of immunosuppression, recent
  • history of angina, myocardial infarction or CVA, since they suppose a confusion factor when elevating the serum levels of the biomarkers,
  • antecedents of acute inflammatory processes or recent traumatisms, suffer chronic ingestion of non-steroidal anti-inflammatory drugs
  • (NSAIDs) or glucocorticoids, decrease the immune and inflammatory response, have taken antibiotics in the last three months, since they decrease the inflammatory activity and therefore the serum levels of
  • biomarkers.

研究者

发起方
Clinica Dental AndreuDental

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