Effect of beta-hydroxy beta-methylbutyrate, arginine and glutamine on complication after cardiac surgery
Not Applicable
Recruiting
- Conditions
- cardiac surgery patients.
- Registration Number
- IRCT20120913010826N31
- Lead Sponsor
- Yazd University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Willingness to cooperate and complete the informed consent form by the patient
Age 18 to 70 years
Body mass index (BMI) above 18.5 and below 30
Do not take supplements or formulas to strengthen the immune system before starting the study
No infection and sepsis
No need for other entral formulas due to special problems (kidney, lung, liver, etc)
Candidate patients for heart surgery
Exclusion Criteria
Drugs that affect metabolism such as steroids and male and female hormonal drugs or corticosteroids
Abnormal liver function
Metastatic cancer and autoimmune diseases
Patients with thyroid, pituitary and hypothalamus dysfunction
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Biochemical evaluation of interleukin 1 (mean serum interleukin-1 concentration) Biochemical evaluation of interleukin 6 (mean serum interleukin-1 concentration) Biochemical evaluation of TNF-alpha (mean serum TNF-alpha concentration). Timepoint: Before and after of surgery. Method of measurement: Biochemical experiments.
- Secondary Outcome Measures
Name Time Method Duration of hospitalization in ICU and hospital. Timepoint: After cardiac surgery. Method of measurement: Check the patient file.