Effect of beta-hydroxy-beta-methylbutyrate (HMB) enriched oral nutrition supplement on surgical outcomes and physical performance in colorectal cancer patients: a randomized Controlled Trial
Recruiting
- Conditions
- colorectal cancer patients who underwent elective colorectal cancer surgerycolorectal cancer, beta-hydroxy-beta-methylbutyrate (HMB) enriched oral supplement, Enhanced Recovery after Surgery (ERAS), physical performance
- Registration Number
- TCTR20220606005
- Lead Sponsor
- Siriraj hospital Mahidol university
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 52
Inclusion Criteria
1. age more than 18 years old ,Diagnosed of colorectal cancer
2. Nutritional risk score (NRS) more than or equal 3
3. Underwent elective colectomy and/or proctectomy at Colorectal unit, General surgery division, Department of surgery, Siriraj hospital Mahidol university
4. able to communicate and agree to participate in the study
Exclusion Criteria
1. uninformed his/her diagnosis of colorectal cancer
2. non colorectal resection procedure eg. proximal colostomy, colonic stenting
3. Emergency colorectal cancer surgery eg. perforate, obstruction
4. pregnancy
5. unable to communicate or walk eg. stroke, bed ridden, cognitive impairment etc.
6. limb amputation
7. GFR <30
8. Dysphagia
9. cow milk allergy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method physical performance 1 month Short Physical Performance Battery (SPPB),physical performance 1 month Handgrip strength test ,Bioelectrical Impedance Analysis (BIA) 1 month Bioelectrical Impedance Analysis (BIA)
- Secondary Outcome Measures
Name Time Method quality of life 1 month EQ-5D-5,surgical outcomes 1 month in-patient record