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Clinical Trials/NCT05984095
NCT05984095
Completed
N/A

Pelvic Floor Rehabilitation in Females With Multiple Sclerosis: Comparison of Two Telerehabilitation Protocols

University of Trieste1 site in 1 country28 target enrollmentSeptember 15, 2023

Overview

Phase
N/A
Intervention
Not specified
Conditions
Multiple Sclerosis
Sponsor
University of Trieste
Enrollment
28
Locations
1
Primary Endpoint
Perceived quality of life
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The goal of this clinical trial is to compare the effects of two different pelvic floor telerehabilitation protocols on selected measures of quality of life and health in females with relapsing-remitting Multiple Sclerosis (rrMS). The main questions it aims to answer are:

  • Is telerehabilitation sufficient to improve quality of life and health in females with rrMS, in particular dedicated to pelvic floor training?
  • Are self-administered training protocols or remotely-supervised training protocols equally effective?

Participants will be randomized to two intervention groups: a self-administered training protocol (SELF) and a remotely-supervised (REMOTE) training protocol. Both protocols will consist in 10 sessions of pelvic floor training lasting 45 min each, once every 5 days.

At the start and at the end of the protocol, all participants will complete 6 questionnaires regarding pain, quality of life and health.

Detailed Description

In this study, the authors aim to evaluate the efficacy of two telerehabilitation protocols dedicated to pelvic floor and urogynecological health in females with relapsing-remitting Multiple Sclerosis (rrMS). In particular, the included participants will be randomized to: * SELF protocol: 10 sessions of pelvic floor exercises, self-administered with a set of videos where a physiotherapist showed the different exercises in order to complete a 45 minutes session. * REMOTE protocol: 10 sessions of pelvic floor exercises, remotely conducted and supervised by a physiotherapist with a one-to-one videocall, showing and monitoring the exercises in order to complete a 45 minutes session. One week before the first session and one week after the last session, all the participants will be asked to complete a set of surveys and questionnaires to investigate participants' pain perception, reported quality of life and health-related parameters.

Registry
clinicaltrials.gov
Start Date
September 15, 2023
End Date
November 25, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Alex Buoite Stella

Research fellow

University of Trieste

Eligibility Criteria

Inclusion Criteria

  • diagnosis of relapsing remitting Multiple Sclerosis confirmed by a neurologist and based on the McDonald criteria from not less than 1 y
  • EDSS \<4.5
  • self reported symptoms of urinary incontinency

Exclusion Criteria

  • females in menopause
  • previous history of bladder or urogynaecological surgery
  • previous history of major abdominal surgery
  • females with a delivery \< 6 months from the start of the study
  • BMI \> 30

Outcomes

Primary Outcomes

Perceived quality of life

Time Frame: At baseline (1 week prior the first telerehabilitation session) and after the protocol (1 week after the last telerehabilitation session)

Evaluation of the perceived quality of life with the Short Form Health Survey 36 (SF-36, 0-100 for each domain, higher the score better the quality of life)

Pain perception

Time Frame: At baseline (1 week prior the first telerehabilitation session) and after the protocol (1 week after the last telerehabilitation session)

Quantification of the perceived pain with a numeric rating scale (NRS, score 0-10 where 10 means unbearable plain), and a body chart

Depression symptoms

Time Frame: At baseline (1 week prior the first telerehabilitation session) and after the protocol (1 week after the last telerehabilitation session)

Evaluation of depression symptoms with the Beck Depression Inventory Scale (BDI, 0-63, higher the score worse the depression)

Sexual health

Time Frame: At baseline (1 week prior the first telerehabilitation session) and after the protocol (1 week after the last telerehabilitation session)

Evaluation of the perceived sexual health with the female sexual function index (FSFI, 1-5 for each item, greater score indicating greater levels of sexual functioning)

Urinary incontinence symptoms

Time Frame: At baseline (1 week prior the first telerehabilitation session) and after the protocol (1 week after the last telerehabilitation session)

Evaluation of urinary incontinence symptoms with the International Consultation on Incontinence Questionnaire (ICIQ, 0-21, higher the score worse the symptoms)

Study Sites (1)

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