Effects of dexmedetomidine on sleep characteristics in mechanically ventilated patients.
Not Applicable
- Conditions
- Mechanically ventilated patients.
- Registration Number
- JPRN-UMIN000002301
- Lead Sponsor
- Emergency and Critical Care Medicine Tokushima University Hospital
- Brief Summary
24-hour PSG was recorded in ten adult MV patients. Total sleep time (TST) during the 24-hour period was 11.4h. During the nighttime, the sleep architecture consisted of non rapid-eye movement (NREM) sleep stage 1 (median 28.9 % of TST), stage 2 (median 71.2 % of TST), stage 3+4 (median 0 % of TST), and REM sleep (median 0 % of TST). The median sleep time totaled 4.7 h during the 9 hour nighttime period and excessive sleep fragmentation was detected by a high frequency of arousal (median 9.3 /h).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
Exclusion criteria were the presence of psychiatric illness, anoxic brain injury, suspected encephalopathy (drug overdose, hepatic failure), seizure disorder, and severe hemodynamic instability.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method