The Disease Severity In Patients With Psoriasis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Psoriasis
- Sponsor
- Universitas Sebelas Maret
- Enrollment
- 33
- Locations
- 1
- Primary Endpoint
- Gamma-Glutamyl Transferase
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
This observational study aims to evaluate new markers to predict disease activity in psoriasis. The main question is SGOT, SGPT, GGT, hs-CRP, and apo B related to disease severity in psoriasis.
Detailed Description
Psoriasis patients who had signed an informed consent were assessed for PASI scores and 5 cc of blood was drawn for GGT, hs-CRP, and apo B examinations. A PASI score is a tool used to measure the severity and extent of psoriasis. PASI is an acronym for Psoriasis Area and Severity Index.
Investigators
Nurhasan Agung Prabowo, MD
Head of Hospital Research Unit
Universitas Sebelas Maret
Eligibility Criteria
Inclusion Criteria
- •Clinical diagnosis of Psoriasis
Exclusion Criteria
- •Heart Failure
- •Diabetes Mellitus
- •Kidney Disease
Outcomes
Primary Outcomes
Gamma-Glutamyl Transferase
Time Frame: only in admission
Gamma-Glutamyl Transferase was check in admission, reference range for adults is 5 to 40 U/L (units per liter)
Apolipoprotein B
Time Frame: only in admission
Apolipoprotein B (ApoB) is the primary apolipoprotein and is the carrier for the following lipids: chylomicrons, low-density lipoprotein ( LDL), very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), and lipoprotein. Unit used in mg/dL
High-sensitivity c-reactive protein
Time Frame: only in admission
High-sensitivity C-reactive protein (hsCRP) is a marker of inflammation that predicts incident myocardial infarction, stroke, peripheral arterial disease, and sudden cardiac death. Unit used in mg/L
PASI
Time Frame: only in admission
A PASI (The Psoriasis Area and Severity Index) score can range from 0 to 72