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Efficacy of Short Hydration for Intermediate to High-Dose Cisplatin-Based Chemotherapy for Outpatient

Phase 2
Active, not recruiting
Conditions
cancer patients who treated with intermediate to high dose cisplatin in outpatient.
Short hydration
cisplatin
Nephrotoxicity
chemoprevention
Registration Number
TCTR20210128002
Lead Sponsor
Division of Medical Oncology, Department of Internal Medicine, Buddhasothorn Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Active, not recruiting
Sex
All
Target Recruitment
13
Inclusion Criteria

1.cancer patients who treated with intermediate to high dose cisplatin in outpatient
2.age > 18 year
3.ECOG performance status 0-2
4. adequate renal function eGFR>60 mL/min

Exclusion Criteria

1. underlying heart disease ,poor LV function
2.eGFR decline >20% from baseline after cisplatin administration

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
nephrotoxicity week 3, week6,week9,week12, week 15 after enroll eGFR
Secondary Outcome Measures
NameTimeMethod
/A N/A N/A
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