Comparisons between 5-Hour Preprocedural hydration vs 20-Hour Preprocedural hydration on Serum Creatinine in Patients with Renal Insufficiency Undergoing an Elective Coronary Procedure

Not Applicable

• Conditions: chronic kidney disease

• Registration Number: JPRN-UMIN000005557
• Lead Sponsor: Oita Nakamura Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2011-04-01
• Study Start: 2011-05-06
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Not provided

Exclusion Criteria

Exclusion criteria were as follows: emergency coronary arteriography or percutaneous coronary intervention, allergy to contrast mediums, pregnancy, intravascular administration of contrast mediums within the preceding 5 days of the study, acute coronary syndrome within the preceding 1 month of the study, severe symptoms of heart failure (New York Heart Association functional class IV), left ventricular ejection fraction <25%, severe hepatic insufficiency, severe chronic respiratory disease, single function kidney, dialysis, and administration of N-acetylcysteine, theophylline, dopamine, or mannitol.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary endpoint was the absolute and % maximal changes in serum creatinine from the baseline up to 48 hours after contrast exposure.

Secondary Outcome Measures

Name	Time	Method
The secondary endpoints were the incidence of CIN defined as a ≥25% increase in serum creatinine within 48 hours.