Observational Study of the Efficacy of Ketamine for Rescue Analgesia in the Post Anesthesia Recovery Room
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 143
- 试验地点
- 1
- 主要终点
- Reduction in pain score after ketamine use in PACU
研究概览
简要总结
Observational study to assess efficacy of IV ketamine bolus when used in the post anesthesia recovery unit for uncontrolled pain despite use of opioids.
详细描述
In this observational study, the investigators will monitor all patients with significant pain after any non-cardiac surgical intervention at the University of Alberta Hospital.
After receiving an adequate dose of potent opioids (hydromorphone, morphine), the participants will receive up to 0,2-0,25 mg/kg IV ketamine bolus. In our center these boluses are given with 10-20mg increments.
The adequate dose of opioids will be determined by the attending anesthesiologist, depending on what patients received intraoperatively and on their comorbidities.
Pain scores will be assessed before and after administration of this drug. The incidence of any side effect after ketamine administration will be documented.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adult patients undergoing non cardiac surgery at University of Alberta Hospital meeting the following criteria:
- •significant pain despite narcotics used in post-anesthesia care unit
- •ketamine ordered by attending anesthesiologist
排除标准
- •Patient refusal to receive ketamine
- •Patients undergoing cardiac surgery
- •Patients who received no narcotics
- •Contra-indication to receiving ketamine (determined by attending anesthesiologist)
研究组 & 干预措施
Patients with significative post-operative pain despite
Patients with significant pain despite receiving narcotics in PACU will receive a bolus dose of IV ketamine to assess its efficacy for pain score reduction. Bolus doses are given by 10mg IV increments, to reach approximate dose of 0,25mg/kg.
干预措施: Ketamine (Drug)
结局指标
主要结局
Reduction in pain score after ketamine use in PACU
时间窗: in the immediate post-operative period in recovery room
The Numeric Rating Scale (NRS-11) is an 11-point scale for patient self-reporting of pain. It is what is used most often in our recovery room for pain assessment. A score of 0/10 means no pain, and 10/10 means worst pain.
次要结局
- Incidence of side effects after ketamine use(in the immediate post-operative period in recovery room)