NCT03690622已完成4 期
The Effect of Topical Dexmedetomidine (0.0055%) on Intraocular Pressure in Healthy Eyes: a Randomized Controlled Trial
Beirut Eye Specialist Hospital1 个研究点 分布在 1 个国家目标入组 49 人开始时间: 2017年12月1日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 49
- 试验地点
- 1
- 主要终点
- Intraocular pressure change
研究概览
简要总结
Evaluate the short-term safety and efficacy of dexmedetomidine (0.0055%) drops on intraocular pressure (IOP) in healthy eyes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
盲法说明
masking for the drop instilled
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients with healthy eyes and no history of glaucoma
排除标准
- •history of glaucoma, IOP > 24mmHg at baseline, abnormal optic nerve on fundus examination, keratoconus, corneal graft, corneal edema or a history of refractive surgery
研究组 & 干预措施
BSS
Sham Comparator
Balanced salt solution
干预措施: Balanced salt solution (Drug)
Dexmedetomidine
Active Comparator
dexmedetomidine (0.0055%)
干预措施: Dexmedetomidine (Drug)
结局指标
主要结局
Intraocular pressure change
时间窗: at presentation, 30 minutes, 4 hours and 24 hours after instillation
Taken by aplanation tonometry
次要结局
未报告次要终点
研究者
研究点 (1)
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