Effect of Topical Dexmedetomidine on Intraocular Pressure

Phase 4

Completed

• Conditions: Intraocular Pressure; Glaucoma
• Interventions: Drug: Balanced salt solution; Drug: Dexmedetomidine

• Registration Number: NCT03690622
• Lead Sponsor: Beirut Eye Specialist Hospital

Brief Summary

Evaluate the short-term safety and efficacy of dexmedetomidine (0.0055%) drops on intraocular pressure (IOP) in healthy eyes.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-12-01
• Primary Completion: 2018-01-01
• Study Completion: 2018-04-03
• Status Verified: 2018-09
• Study First Submitted: 2018-09-12
• Study First Submitted QC: 2018-09-28
• Study First Posted: 2018-10-01
• Last Update Submitted: 2018-10-01
• Last Update Posted: 2018-10-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 49

Inclusion Criteria

• Patients with healthy eyes and no history of glaucoma

Read More

Exclusion Criteria

• history of glaucoma, IOP > 24mmHg at baseline, abnormal optic nerve on fundus examination, keratoconus, corneal graft, corneal edema or a history of refractive surgery

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
BSS	Balanced salt solution	Balanced salt solution
Dexmedetomidine	Dexmedetomidine	dexmedetomidine (0.0055%)

Primary Outcome Measures

Name	Time	Method
Intraocular pressure change	at presentation, 30 minutes, 4 hours and 24 hours after instillation	Taken by aplanation tonometry

Trial Locations

Locations (1)

Beirut Eye Specialist Hospital; 🇱🇧 Beirut, Lebanon