Multidimensional and Multimodal Profiling of Oropharyngeal Carcinoma

Recruiting

• Conditions: Human Papilloma Virus; Oropharyngeal Carcinoma

• Registration Number: NCT05880797
• Lead Sponsor: Stanford University

Brief Summary

The purpose of this study is to better understand the natural history of oropharyngeal carcinoma (OPC), with or without an association with the human papilloma virus (HPV). For this study, the investigators plan to collect blood from OPC patients prior to treatment and at six subsequent time points.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-05-17
• Study First Submitted QC: 2023-05-25
• Study First Posted: 2023-05-30
• Study Start: 2023-07-07
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-13
• Last Update Posted: 2025-03-14
• Primary Completion: 2026-08
• Study Completion: 2026-08

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• Patients diagnosed with oropharyngeal carcinoma or patients with cancer of the unknown primary that is HPV associated, or possibly deemed to be originating from the oropharynx.

Exclusion Criteria

• Not willing to sign consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sample collection	up to 36 months post-op	30-50cc of blood

Secondary Outcome Measures

Name	Time	Method
tumor sample	Day 1	tumor sample (FFPE) or fresh tissue post-excision or surgery, this will only be collected, if and when feasible, after the tumor has been removed post procedure.

Trial Locations

Locations (1)

Stanford University; 🇺🇸 Palo Alto, California, United States