Effect of Pitavastatin on Amelioration for Renal Function in Patients with Chronic Kidney Disease
Not Applicable
- Conditions
- Hypercholesterolemia patients evaluated inulin clearance with chronic kidney disease (stage 3)
- Registration Number
- JPRN-UMIN000001600
- Lead Sponsor
- agoya University, Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
(1)Patients whose creatine levels change more than 25% in past 1 year. (2)Patients who are planed to change drugs for CKD. (3)Known hypersensitivity or history of clinically significant adverse reactions to Livalo. (4)Patients with serious hepatopathy or biliary obstruction. (5)Patients who are being treated with cyclosporine. (6)Pregnant, possibly pregnant, or lactating. (7)Patients who do not accept informed consent. (8)Patients who are judged unsuitable for this study by the doctor in charge of that patients.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Amount of change in inulin clearance
- Secondary Outcome Measures
Name Time Method 1)Comparison of a percent and amount change in inulin clearance and eGFR among baseline matched CKD stage3 patients who is under medical care in Nagoya University Hospital without statins prescription 2)A percent change in inulin clearance 3)A percent and amount of change in following factors 1.Serum lipid profile (TC, LDL-C, HDL-C, TG) 2.The laboratory parameters (AST, ALT, gamma-GTP, CK, and the other) 3.The laboratory parameters(RBC, WBC, Ht, and the other) 4.The special laboratory parameters (hs-CRP, 8-OHdG, alpha1 globulin, beta2 globulin, creatine) 5.Urinary protein (Urinary albumin)