MedPath

A pill against anxiety

Recruiting
Conditions
Dental anxiety
Registration Number
NL-OMON28388
Lead Sponsor
Academic Medical Center of the University of Amsterdam
Brief Summary

Brunet A, Orr SP, Tremblay J, Robertson K, Nader K, Pitman RK: Effect of post-retrieval propranolol on psychophysiologic responding during subsequent script-driven traumatic imagery in post-traumatic stress disorder. J Psychiatr Res 2008, 42:503–6. Lonergan MH, Olivera-Figueroa LA, Pitman RK, Brunet A: Propranolol’s effects on the consolidation and reconsolidation of long-term emotional memory in healthy participants: a meta-analysis. J Psychiatry Neurosci 2013, 38:222–31.

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
34
Inclusion Criteria

1. Signed written informed consent

2. Minimum age of 18 years on entry to the study

Exclusion Criteria

1. Asthma or other obstructive pulmonary disease

2. Cardiac failure

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Dental trait anxiety score reduction from baseline to 4-weeks follow-up.
Secondary Outcome Measures
NameTimeMethod
Self-reported anxiety during surgery; physiological parameters (heart rate and blood pressure) during recall of the crucial fear-related memory; self-reported vividness and emotional charge of the crucial fear-related memory.
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