The effects of propranolol on fear of tooth removal: A randomized, placebo-controlled, double-blind, parallel design trial
Completed
- Conditions
- (Dental) anxiety(Dental) phobia1000286110019190
- Registration Number
- NL-OMON45112
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 70
Inclusion Criteria
1. Excessive anxiety for necessary tooth and/or molar extraction
2. Age above 18 years.
Exclusion Criteria
1. Systolic blood pressure < 100mmHg;
2. Allergic asthma, Decompensatio cordis, Cardiac arrythmia or Insulin-dependent diabetes;
3. Previous adverse reaction to a beta-blocking agent;
4. Use of another beta-blocking agent;
5. Pregnant or breast feeding;
6. Being in psychotherapy elsewhere;
7. Renal failure.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>- S-DAI score (short version of the Dental Anxiety Inventory)<br /><br>- emotional intensity and vividness of the traumatic memory that is presumed to<br /><br>have caused the anxiety for tooth extraction</p><br>
- Secondary Outcome Measures
Name Time Method <p>- trauma-related (PTSD) symptom severity on a continuous scale the Dutch<br /><br>version of the Impact of Event Scale (IES; Weiss & Marmar, 1997) will be used.<br /><br>- the number of participants that meets the criteria for a specific phobia for<br /><br>dental treatment (as confirmed by the M.I.N.I. plus questionnaire)<br /><br>- degree of state anxiety<br /><br>- degree of trait anxiety<br /><br>- Physiological parameters; heart frequency and blood pressure</p><br>