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A study to compare the effect of general anaesthesia and intravenous anaesthesia in oral cancer patients for perioperative inflammatio

Not Applicable
Conditions
Health Condition 1: O- Medical and Surgical
Registration Number
CTRI/2022/11/047067
Lead Sponsor
All India Institute of Medical Sciences Jodhpur
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1.All patients with ASA grade 1, 2

2.Patients of either sex

3.Age 18 to 60 years

4.Patients expected to get extubated in immediate postoperative period

Exclusion Criteria

1. Patients refusal to participate in the study or giving consent

2. Patients with ASA grade >2

3. Patients having chronic pain or any opioid treatment

4. Patient requiring postoperative ventilation support

5. Patient with any other local or systemic infection

6. Patient with sepsis or septic shock

7. Patients on beta blockers or having bradycardiaor hypotension

8. Patient with BMI 35kg/m2

9. Patients planned for free flap reconstrucion

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To compare change in value of TNF alphaTimepoint: day 1
Secondary Outcome Measures
NameTimeMethod
1.To compare change in value of IL6,IL 10, IL 13. <br/ ><br>2.To compare Change in value of TNF at day 3 <br/ ><br>3. total analgesic need in both the groups at Day2 <br/ ><br>Timepoint: Day 1,2 and 3
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