A study to find out the efficiency of pain relief in using esmolol as an adjunct to morphine in breast surgeries.
Phase 4
Completed
- Conditions
- Health Condition 1: null- Carcinoma Breast
- Registration Number
- CTRI/2018/05/013571
- Lead Sponsor
- Government Medical College Kozhikode
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 140
Inclusion Criteria
Patients undergoing Modified Radical Mastectomy falling into ASA criteria 1 & 2
Exclusion Criteria
Male patients for mastectomy
IHD
Bronchial asthma
Bradycardia
Lung disease
Cardiac failure
Patients taking analgesic drugs regularly for other reasons
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the analgesic efficacy of esmolol given perioperatively in patients undergoing mastectomy under general anesthesia in terms of : <br/ ><br>1)numerical rating scale for pain assessment <br/ ><br>2)time to demand for first rescue analgesic <br/ ><br>3)the number of bolus doses and total opioid consumption in 24 hrs postoperatively.Timepoint: 10 minutes, 2 hours, 6 hours, 12 hours, 24 hours post operatively
- Secondary Outcome Measures
Name Time Method To evaluate the hemodynamic stability, any side effects like bradycardia and hypotension.Timepoint: Within 24 hours post surgery