The developmental and implantation potential of aneuploid and mosaic human embryos, as assessed in an in vitro model
Completed
- Conditions
- embryo aneuploidy100002111008362410013356
- Registration Number
- NL-OMON33807
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 110
Inclusion Criteria
Participation in study CCMO NL18499.000.07
Exclusion Criteria
No surplus embryos available
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>- In-vitro development: (early arrested, late arrested or developing), and in<br /><br>vitro implantation: invaded, attached or not-attached.<br /><br>- Total number of embryonic cells,proportion of aneuploid cells, and relative<br /><br>distribution between inner cell mass and trophoblast on day 10 after extended<br /><br>culture.</p><br>
- Secondary Outcome Measures
Name Time Method <p>- Correlation between cytokine/trophic factor patterns expressed in<br /><br>(co-)culture media and the quality of development in vitro (early arrested,<br /><br>late arrested and developing embryos).</p><br>