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临床试验/NL-OMON20480
NL-OMON20480招募中不适用

ANTIBIOTIC EXPOSURE AT THE INFECTION SITE IN PERIPROSTHETIC JOINT INFECTIONS

Erasmus MC0 个研究点目标入组 120 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
Erasmus MC
入组人数
120

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

入选标准

  • Age = 18 years.
  • -Written informed consent has been obtained from the patient
  • -Suffering from periprosthetic (hip or knee) joint infections and therefore treated with one of the following antibiotics as part of the two-stage arthroplasty exchange:
  • oIV: vancomycin, flucloxacillin or cefuroxime
  • oOral: flucloxacillin, clindamycin or co-trimoxazole
  • -Patients undergoing a two-stage implant exchange of hip or knee with or without antibiotic free interval prior to re-implantation.
  • -Able and willing to undergo joint punctures and venous blood sampling during and, in case of an antibiotic free interval, at the end of the six-weeks antibiotic treatment.

排除标准

  • -Unable to draw samples for study purposes.
  • -Language barriers.
  • -The use of the target antibiotics at the start of study participation (and therefore at the start of the antibiotic treatment as part of the two-stage arthroplasty exchange).
  • -The use of drugs interacting with the target antibiotics.

研究者

发起方
Erasmus MC

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