NL-OMON54617招募中不适用
Antibiotic exposure at the infection site in periprosthetic joint infections - ASTERICS
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 120
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Age >= 18 years.
- •- Written informed consent has been obtained from the patient or their legally
- •authorized representative.
- •- Suffering from periprosthetic (hip or knee) joint infections and therefore
- •treated with one of the following antibiotics as part of the one-stage wo-stage
- •arthroplasty exchange:
- •IV: vancomycin, flucloxacillin or cefuroxime
- •Oral: flucloxacillin, clindamycin or co-trimoxazole or ciprofloxacine
- •- Patients undergoing a two-stage implant exchange of hip or knee with or
- •without antibiotic free interval prior to re-implantation.
- •- Able and willing to undergo joint punctures and venous blood sampling during
- •and, in case of an antibiotic free interval, at the end of the six-weeks
- •antibiotic treatment.
排除标准
- •- Unable to draw samples for study purposes; Except when a patient received a
- •vancomycin-loaded spacer, then they will remain included.
- •- Language barriers.
- •- The use of the target antibiotics at the start of study participation (and
- •therefore at the start of the antibiotic treatment as part of the two-stage
- •arthroplasty exchange).
- •- The use of drugs interacting with the target antibiotics.
研究者
相似试验
招募中
不适用
ANTIBIOTIC EXPOSURE AT THE INFECTION SITE IN PERIPROSTHETIC JOINT INFECTIONSOrthopedic infectionsNL-OMON20480Erasmus MC120
尚未招募
Unknown
Antibiotic penetration into the pleural space in patients with pleural empyemaJ86.9J86Pyothorax without fistulaPyothoraxDRKS00034732niversitätsklinikum Augsburg25
尚未招募
不适用
Precision use of Antibiotics in Infected Necrotizing Pancreatitisacute pancreatitisNL-OMON56749Amsterdam UMC306
尚未招募
不适用
Study of common organisms causing and effective drugs againest them in lacrimal sac infection in adultsCTRI/2021/03/031959Srikiran Institute Of Ophthalmology
进行中（未招募）
1 期
Concentrations of antibiotics in the lung in mechanically ventilated critically ill patients: example meropenempneumoniacomplicated urinary infectioncomplicated abdominal infectioncomplicated skin and soft tissue infectionacute bacterial meningitisMedDRA version: 20.0Level: LLTClassification code 10049582Term: Soft tissue infection NOSSystem Organ Class: 100000004862MedDRA version: 20.0Level: LLTClassification code 10040874Term: Skin infection NOSSystem Organ Class: 100000004862MedDRA version: 20.0Level: LLTClassification code 10046576Term: Urinary tract infection, site not specifiedSystem Organ Class: 100000004862MedDRA version: 22.1Level: LLTClassification code 10035725Term: Pneumonia NOSSystem Organ Class: 100000004862MedDRA version: 20.1Level: LLTClassification code 10056570Term: Intra-abdominal infectionSystem Organ Class: 100000004862EUCTR2012-000443-27-DEDept. of Anesthesiology and Intensive Care, Charité - Campus Benjamin Franklin20