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Effects of Jing Si Herbal Tea on Quality of Life and Sleep in Dementia and Their Caregivers

Not Applicable
Not yet recruiting
Conditions
Dementia
Quality of Life
Caregiver Burden
Interventions
Dietary Supplement: Jing Si Herbal Tea
Dietary Supplement: Barley Tea
Registration Number
NCT06198699
Lead Sponsor
National Cheng Kung University
Brief Summary

Jing Si Herbal Tea has been found to be effective in improving health for the conditions of cancers, aging, depression, and sleep. Such evidence has been shown in animal models and clinical research with publications in the international journals. However, empirical evidence regarding the effectiveness of Jing Si Herbal Tea for patients with dementia and their caregivers on their quality of life and psychosocial health remains unclear. Therefore, the present project aims to investigate the feasibility of taking Jing Si Herbal Tea among patients with dementia; then, to investigate if Jing Si Herbal Tea could improve quality of life and psychosocial health for patients with dementia and their caregivers. The project will be three years. The first year will examine the feasibility for the patients with dementia. A total of 100 patients with dementia will be recruited and they will be informed to take the Jing Si Herbal Tea two times per day (one time in the morning and another time in the afternoon). All the participants will be measured for their quality of life and psychosocial health at baseline, three months after baseline, and six months after baseline, to have initial evidence of the improvements in quality of life and psychosocial health without having a control group. The second year will recruit 200 patients with dementia and randomly assign them into a treatment group (taking Jing Si Herbal Tea) and a control group (taking placebo). All the participants will be measured for their quality of life and psychosocial health at baseline, three months after baseline, and six months after baseline, to investigate the strong evidence of Jing Si Herbal Tea on quality of life and psychosocial health. The third year will recruit 200 caregivers of patient with dementia and randomly assign them into a treatment group (taking Jing Si Herbal Tea) and a control group (taking placebo). All the participants will be measured for their quality of life and psychosocial health at baseline, three months after baseline, and six months after baseline, to investigate the strong evidence of Jing Si Herbal Tea on quality of life and psychosocial health.

Detailed Description

Not available

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
All
Target Recruitment
400
Inclusion Criteria
  • diagnosis of dementia
  • 50 years or older
  • with sufficient cognition to complete the questionnaires
  • can communicate using Mandarin or Taiwanese
Exclusion Criteria
  • with renal function problems
  • not suitable for Jing Si Herbal Tea after evaluation from a psychiatrist/physician
  • with the condition of change the commencement of guardianship (or commencement of assistance)

For caregivers:

Inclusion Criteria:

  • caregivers of people with dementia for more than half years
  • 20 years or older
  • with sufficient cognition to complete the questionnaires
  • can communicate using Mandarin or Taiwanese

Exclusion Criteria:

  • with renal function problems
  • not suitable for Jing Si Herbal Tea after evaluation from a psychiatrist/physician
  • with the condition of change the commencement of guardianship (or commencement of assistance)

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Jing Si Herbal Tea GroupJing Si Herbal TeaFrequency: Two times of herbal tea (one in the morning; one in the afternoon) per day Duration: Consumption for three months Dosage: One pack (14g) with 600 ml water for each time of herbal tea consumption
Barley Tea GroupBarley TeaFrequency: Two times of barley tea (one in the morning; one in the afternoon) per day Duration: Consumption for three months Dosage: 600 ml each time of barley tea consumption
Primary Outcome Measures
NameTimeMethod
Insomnia Severity Index [for both people with dementia and their caregivers]baseline; 3 months after baseline; 6 months after baseline

sleep problem measure; score range 0-28; higher score indicates more severe insomnia

World Health Organization Quality of Life Assessment for age (WHOQOL-AGE) [for people with dementia]baseline; 3 months after baseline; 6 months after baseline

quality of life measure; score range 13-65; higher score indicates better quality of life

World Health Organization Quality of Life Assessment brief version (WHOQOL-BREF) [for caregivers]baseline; 3 months after baseline; 6 months after baseline

quality of life measure; score range 4-20; higher score indicates better quality of life

Secondary Outcome Measures
NameTimeMethod
5 items of Geriatric Depression Scale [for people with dementia and their caregivers]baseline; 3 months after baseline; 6 months after baseline

depression measure; score range 0-5; higher score indicates greater depression

Short Portable Mental Status Questionnaire [for people with dementia]baseline; 3 months after baseline; 6 months after baseline

cognition measure; score range 0-10; higher score indicates poor cognition

Katz Index of Independence in Activities of Daily Living [for people with dementia]baseline; 3 months after baseline; 6 months after baseline

activities of daily living function measure; score range 0-6; higher score indicates better activities of daily living

Clinical Frailty Scale [for people with dementia]baseline; 3 months after baseline; 6 months after baseline

frailty measure; score range 1-9; higher score indicates more frail

12 item of Zarit Burden Interview [for caregivers]baseline; 3 months after baseline; 6 months after baseline

caregiver burden measure; score range 0-48; higher score indicates greater burden

Integrated care for older people [for people with dementia]baseline; 3 months after baseline; 6 months after baseline

intrinsic capacity measure; score range 0-13; higher score indicates poorer intrinsic capacity

Depression, Anxiety, Stress Scale-21 [for people with dementia and their caregivers]baseline; 3 months after baseline; 6 months after baseline

psychological distress measure; score range 0-63; higher score indicates greater distress

Attitude and Thoughts Toward Older People Scale [for people with dementia and their caregivers]baseline; 3 months after baseline; 6 months after baseline

ageism measure; score range 17-85; higher score indicates higher level of ageism

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