Establishment of treatment regimen to eradicate H. pylori infection in patients who failed 1st-line and 2nd-line therapy.
Not Applicable
- Conditions
- Helicobacter pylori-associated gastritis
- Registration Number
- JPRN-UMIN000013594
- Lead Sponsor
- Hirosaki University Graduate School of Medicine
- Brief Summary
The eradication rate of PCAB-AMOX-STFX was 85.7% (42/49; 95% CI, 75.9-95.5%) by intention-to-treat analysis and 87.5% (42/48; 78.4-96.9%) by per protocol analysis. Eradication was unsuccessful in one of two patients whose strains had low sensitivity to AMOX and three patients whose strains were resistant to STFX In contrast, eradication therapy was successful in 13 patients infected with strains which were sensitive to both AMOX and STFX.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Not provided
Exclusion Criteria
who did not agree
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eradication rate
- Secondary Outcome Measures
Name Time Method side effects