Comparison of toothpaste containing fluoride associated or not with arginine in initial caries lesions in milk teeth
Not Applicable
Recruiting
- Conditions
- Dental caries, Dental caries susceptibility, Tooth demineralization
- Registration Number
- RBR-2g9vbx
- Lead Sponsor
- niversidade Cruzeiro do Sul
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Healthy children; aged 4 and 5 years old; both genders; resident in the city of São Paulo (public water fluoridation); present at least one visible active white spot lesion on smooth surface of maxillary anterior primary teeth (ICDAS 2); present signed Parent-Guardian Informed Consent Statement
Exclusion Criteria
Children who participated of previous research over the past 3 months; using orthodontic devices; with cognitive impairment or syndromes; using medication; receiving dental treatment with professional topical fluoride application (varnish, gel or mousse); children who not allow clinical examination
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary outcome: Area of the white spot lesion verified by standardized digital photographic method from the observation of a variation in mm2 during measurements performed at baseline and after 3 months of the intervention. Progression, regression or stability of the area of the white spot lesion will be evaluated after 3 months of the intervention.<br>
- Secondary Outcome Measures
Name Time Method Secondary outcome: Reduction of the fluorescence values of the white spot lesion verified by a laser fluorescence device (DIAGNOdent pen) from the observation of a variation in number (from 0 to 99) during measurements performed at baseline and after 3 months of the intervention.;Secondary outcome: Evaluation of caries activity (active or inactive) of white spot lesion verified by visual inspection from the observation of an optical (opacity or brightness) and tactile (roughness or smoothness) variation during assessments performed after 3 months of the intervention.;Secondary outcome: Evaluation of global caries experience of the children assessed by dmft index at baseline and after 3 months of the intervention.