A study to find out if Homoeopathy With and Without Chelidonium can help reduce joint pain and stiffness

Phase 4

Recruiting

Conditions: Osteoarthritis of knee,

Registration Number: CTRI/2025/06/088016

Lead Sponsor: Venkateswara Homoeopathic Medical College and Hospital , Chennai

Brief Summary: **Background:** Osteoarthritis (OA) is a long-term joint condition thatcauses pain, stiffness, and reduced mobility, often affecting a person’s dailylife. Homoeopathy offers a gentle, holistic approach to managing such chronicconditions. Chelidonium Majus Q, a well-known homoeopathic mother tincture, hastraditionally been used to address hepatic disorders, this study explores howeffective Chelidonium Majus Q when given along with individualized Homoeopathicmedicine in review with Homoeopathic Materia medica is in relieving thesymptoms of Osteoarthritis of the knee.

**Objective:** This study is intended to determine and evaluate theeffectiveness of Chelidonium Majus in mother tincture form in reduction of painand stiffness in patients with Osteoarthritis, and to compare the WOMAC scores and Visual Analogue Scale of both groups to determine statistical significance.

**Methodology:** This Randomized clinical study of 60 cases involving twogroups, 30 cases each. GROUP 1 cases managed with individualized homoeopathicmedicine and Chelidonium majus Q, GROUP 2 cases managed with individualizedhomoeopathic medicine only. The results obtained will be statisticallyanalyzed and evaluated by using Paired ‘T’ test in order to determine theeffectiveness of Chelidonium majus Q in symptomatic relief of Osteoarthritis ofthe knee. This study provides evidence to say that, Chelidonium majus in theform of mother tincture have significant results in lowering the pain and jointstiffness, and improves the mobility of the affected knee in Osteoarthritispatients.

**Expected Outcome:** This study anticipates demonstrating that Patientsadministered with Chelidonium majus q along with Individualized homoeopathicmedicine will show significant reduction in pain and stiffness of joint, which is assessed through WOMAC scale and Visual Analogue Scale

Detailed Description: Not available

Recruitment & Eligibility

Status: Open to Recruitment

Sex: All

Target Recruitment: 60

Inclusion Criteria

patients diagnosed with Osteoarthritis of Knee with Western Ontario McMaster Universities Arthritis Index score of more than 40.
Patients with Visual Analogue Scale of more than 4.

Exclusion Criteria

Rheumatoid arthritis, psoriatic arthritis, Gout.
patients with any other disease affecting mobility, patients with severe systemic illness such as liver and kidney dysfunction, diabetes, cardio vascular disease, patients on long term NSAIDS or steroids,.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
WOMAC score	Baseline and after 12 weeks

Secondary Outcome Measures

Name	Time	Method
Visual Analogue Score, joint stiffness and physical functions of the patient	baseline ,2weeks, 4 weeks, 6 weeks,8weeks, 10 weeks, 12 weeks

Trial Locations

Locations (1): Venkateswara Homeopathic Medical College and Hospital
🇮🇳
Chennai, TAMIL NADU, India
Venkateswara Homeopathic Medical College and Hospital
🇮🇳Chennai, TAMIL NADU, India
Dr S SANDHYA
Principal investigator
9841002329
drsandhyakalidas@yahoo.in