Muscle Growth and Development Following a 12-week Resistance Training Program in Men and Women Consuming Soy and Whey Protein Supplements
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 61
- Locations
- 2
- Primary Endpoint
- Lean Body Mass Change
Study Overview
Brief Summary
Soy and whey protein have different concentrations of leucine, an amino acid known to be a particularly potent simulator of muscle protein synthesis. The purpose of this study is to determine whether matching soy and whey protein supplements for leucine content instead of by total protein content would contribute to differences in strength increases and muscle growth in response to 12 wk of resistance training.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Other
- Masking
- Double (Participant, Investigator)
Eligibility Criteria
- Ages
- 18 Years to 35 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •non-smoking
- •body mass index (BMI) 18.5-24.9
- •recreationally active
Exclusion Criteria
- •participated in structured weight training during the previous 12 month
- •vegetarian or vegan
- •presence of chronic disease
- •pregnant, postpartum up to six months, lactating, or intention to become pregnant
- •allergy to whey or soy
- •changes in body weight more than 10 pounds in the past three months
Outcomes
Primary Outcomes
Lean Body Mass Change
Time Frame: Post-12 week intervention
assessed using dual energy x-ray absorptiometry (DEXA) scan for changes in lean body mass (kg)
Leg Girth Changes
Time Frame: Post-12 week intervention
assessed using circumference measurements (cm)
Muscle Tissue Thickness Change
Time Frame: Post-12 week intervention
assessed using changes in muscle thickness assessed by ultrasound (cm)
Secondary Outcomes
- Change in Peak Torque When Doing Leg Extensions(Post-12 week intervention)
Investigators
Heidi Lynch
Assistant Professor
Point Loma Nazarene University