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Treatment of fungal infection of skin with two antifungal drugs (terbinafine and itraconazole)

Phase 3
Conditions
Health Condition 1: L088- Other specified local infections of the skin and subcutaneous tissue
Registration Number
CTRI/2018/09/015843
Lead Sponsor
Institute of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Clinically suspected tinea corporis, tinea cruris or tinea faciei or any combination of these

2. Confirmation of tinea by KOH microscopy

Both criteria should be met.

Exclusion Criteria

1. Pregnancy

2. Lactation

3. Presence of any other type of tinea e.g. onychomycosis

4. Another skin disease at the site of tinea

5. Inability to come for follow ups

6. Intake of terbinafine or itraconazole in last 1 month

7. History of drug reaction or allergy to terbinafine or itraconazole

8. Present history of liver, renal or ischemic heart disease

9. Patients on treatment with drugs that have interaction with terbinafine or itraconazole

10. Patients requiring antihistamines due to co-existing skin disease e.g. urticaria

11. Abnormal complete blood count (for hemoglobin value taken as abnormal will be <9 g/dl, for platelet count <1 lac/microliter), liver function tests, or renal function tests

Any one criteria will exclude the patient.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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