NCT00000293CompletedPhase 3
Effect of Nefazodone on Relapse in Females With Cocaine Abuse
Conditions
Drugs
Trial Snapshot
- Phase
- Phase 3
- Status
- Completed
- Locations
- 1
- Primary Endpoint
- Retention
Study Overview
Brief Summary
The purpose of this study is to determine the effect of nefazodone on relapse to cocaine use in depressed and non-depressed females with cocaine abuse/dependence.
Detailed Description
The purpose of this study is to determine the effect of nefazodone on relapse to cocaine in women and if a greater effect will be seen in the dependent condition. A relapse and coping skills questionnaire will be utilized to determine the various factors important to the relapse process.
Study Design
- Study Type
- Interventional
- Primary Purpose
- Treatment
- Masking
- Double
Eligibility Criteria
- Ages
- 18 Years to 55 Years (Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Female, ages 18-55, cocaine abuse/dependence, use of cocaine 7 days of the last 30 days or of the 30 days prior to current abstinence, less than 90 days current abstinence, at least an 8th grade education.
Exclusion Criteria
- •Unstable medical conditions; current use of Hismanal, Seldane, or Propulsid; dx of MR, OBS, bipolar, schizophrenia.
Outcomes
Primary Outcomes
Retention
Depression (secondary)
Primary drug use
Relapse
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
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