Evidence-based Screening Strategies for Celiac Disease
- Conditions
- Celiac Disease
- Registration Number
- NCT03136731
- Lead Sponsor
- Katri Kaukinen
- Brief Summary
Main aim: To find evidence-based screening strategies for celiac disease in high risk groups and to find new biomarkers or biomarker combinations for celiac disease diagnostics and follow-up.
- Detailed Description
The current project will result in the identification of genetic, environmental or downstream biomedical markers that predict the development of celiac disease at the individual level. Moreover, the markers can be exploited in prediction of specific disease risks, manifestations, comorbidities and complications.
Recruitment & Eligibility
- Status
- ENROLLING_BY_INVITATION
- Sex
- All
- Target Recruitment
- 3517
Inclusion Criteria
- Cohort 1: Family member of celiac disease patient
- Cohort 2: Previously diagnosed celiac disease
Exclusion Criteria
- Cohort 1: No previous celiac disease
- Cohort 2: Celiac disease diagnosis not confirmed
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Forthcoming celiac disease diagnosed by current diagnostic criteria With in 10 years Assessed by positive transglutaminase antibodies, small bowel mucosal villous atrophy
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Tampere University Hospital / Tampere University
🇫🇮Tampere, Finland
Tampere University Hospital / Tampere University🇫🇮Tampere, Finland