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Clinical Trials/NCT05472740
NCT05472740
Completed
N/A

Transcutaneous Electrical Nerve Stimulation for Analgesia During Outpatient Endometrial Biopsy: a Randomized Controlled Trial

Duke University1 site in 1 country149 target enrollmentDecember 13, 2022

Overview

Phase
N/A
Intervention
Not specified
Conditions
Endometrial Diseases
Sponsor
Duke University
Enrollment
149
Locations
1
Primary Endpoint
Pain After Endometrial Biopsy, as Measured by Visual Analogue Scale (VAS)
Status
Completed
Last Updated
8 months ago

Overview

Brief Summary

The purpose of this study is to see whether transcutaneous electrical nerve stimulation (or TENS) reduces pain during an endometrial biopsy. A TENS unit is an over-the-counter, FDA approved device that sends low-level electrical impulses through the skin to reduce the amount of discomfort experienced during procedures. A TENS unit is very low-risk and used in a lot of ways, including for chronic pain, after surgery, and during labor. Since there is no standard way of managing discomfort during an endometrial biopsy, the investigators think that TENS might be helpful.

Participating in the study may require some additional time in clinic to answer research-related questions. Subjects will be asked to answer demographic questions (which will be combined anonymously) before and after the procedure, as well as rate subject's pain at different time points during the procedure.

The biggest benefit in participating is that subject's discomfort might be lower during and after the procedure. Subjects may not benefit from participating in this study. There is a small risk of a skin reaction from wearing the TENS pads.

Registry
clinicaltrials.gov
Start Date
December 13, 2022
End Date
December 26, 2023
Last Updated
8 months ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • at least 18 years old
  • undergoing an outpatient endometrial biopsy
  • Duke gynecological oncology clinics and general gynecology clinic

Exclusion Criteria

  • age younger than 18 years
  • unable to follow study instructions and/or independently adjust TENS settings
  • cutaneous damage at the TENS application site
  • pacemaker or automatic implanted cardiac defibrillator
  • inability to understand or declines to sign the informed consent form
  • previous personal experience using a TENS unit
  • concurrent procedure (ex. IUD placement at time of biopsy)
  • pregnant women (will be excluded as part of standard of care for endometrial evaluation)

Outcomes

Primary Outcomes

Pain After Endometrial Biopsy, as Measured by Visual Analogue Scale (VAS)

Time Frame: Immediately after endometrial biopsy

Scores are measured on a 100 mm VAS. The VAS ranges from 0 to 100 mm with the lower score indicating less pain and the higher score indicating greater pain

Secondary Outcomes

  • Measure of the Intervention Acceptability Based on Survey Response(End of procedure)
  • Tolerability of Procedure, as Measured by Visual Analogue Scale (VAS)(End of procedure)
  • Pain, as Measured by Visual Analogue Scale (VAS) Across Different Time Intervals(Speculum placement, tenaculum placement, 5 minutes after biopsy, and 15 minutes after biopsy)
  • Provider Satisfaction With the Procedure(End of procedure)

Study Sites (1)

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