Comparison of two different doses of clonidine as adjuvant to ropivacaine in ultrasound guided transversus abdominis plane block for post caesarean analgesia–A prospective double blinded randomized controlled study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Duration of analgesic effects:
研究概览
简要总结
This study compared two doses of clonidine as an adjuvant to ropivacaine in ultrasound-guided transversus abdominis plane (TAP) blocks for post-caesarean analgesia. Patients receiving the higher clonidine dose experienced longer-lasting pain relief and better analgesic effects, but with increased sedation and mild hemodynamic changes. The lower dose provided effective analgesia with fewer side effects but a shorter duration of pain control. Overall, the study suggests that while higher doses of clonidine enhance analgesia duration, the lower dose offers a safer balance between efficacy and side effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 15.00 Year(s) 至 44.00 Year(s)（—）
- 性别
- Female
入选标准
- •Parturients belonging to American Society of Anaesthesiologist grade II posted for both elective and emergency lower segment caesarean section under Spinal Anaesthesia.
排除标准
- •Patient not willing to participate in the study.
- •Allergic to local anaesthetic agent.
- •Patient BMI more than 30 kg per m
- •Height less than 145cm.
- •Contraindications to Spinal Anaesthesia (Coagulopathies, local infections).
结局指标
主要结局
Duration of analgesic effects:
时间窗: 0mins,30mins,1hour,4hours,8hours,12hours,24hours
It is noted considering the time of completion of the respective block procedure (I.E deposition of the required amount of local anaesthetic drug in to the desired plane) on each side as the reference point to the first rescue analgesia.
时间窗: 0mins,30mins,1hour,4hours,8hours,12hours,24hours
次要结局
- Time for first rescue analgesia and Comparing pain scores using visual analogue scale.(0mins,30mins,1hour,4hours,8hours,12hours,24hours)
研究者
Mirthan krish B
Sri Venkateshwaraa medical college hospital and research center