Improving brain health in at risk populations with aerobic exercise

Not Applicable

• Conditions: Cognitive impairment; Dementia; Neurological - Dementias; Physical Medicine / Rehabilitation - Other physical medicine / rehabilitation

• Registration Number: ACTRN12619000988156
• Lead Sponsor: niversity of Southern Queensland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-07-11
• Study Completion: 2020-02-28
• Last Update Posted: 5 July 2021

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 28

Inclusion Criteria

Be aged 50-80 years
Be physically inactive
Have a body mass index >25 kg/m2 (we will calculate this)
Have blood pressure below 160/100mmHg (we will determine this at the screening visit)
Have an adequate ultrasound signal (we will determine this at the screening visit).
Not have heart, kidney or liver disease (excluding fatty liver disease), cancer or a neurological disorder (e.g. stroke)
Not taking insulin, anticoagulants or hormone replacement therapy

Exclusion Criteria

Cognitive impairment and/or dementia
Less than 150 minutes of moderate to vigorous intensity exercise/week
BMI greater than 25 kg/m2
resting blood pressure equal to or less than 160/100mmHg
Chronic kidney disease
Chronic liver disease (excluding fatty liver disease)
Coronary heart disease
Congestive heart failure
Atrial fibrillation
Prior myocardial infarction
Carcinoma (unless in remission or similar)
Stroke
Aneurysm
Epilepsy
Multiple sclerosis
Parkinson’s disease
Neuropathies
Presence of a fistulae
Smoker
Prescribed insulin, hormone-replacement therapy, oral anticoagulants
Middle cerebral artery signal absent on Doppler ultrasound

Study & Design

• Study Type: Interventional
• Study Design: Not specified