Effects of pravastatin on the prevention of preeclampsia in high-risk pregnant wome
Phase 3
Recruiting
- Conditions
- Pre-eclampsia.Pre-eclampsia
- Registration Number
- IRCT20121224011862N5
- Lead Sponsor
- Vice chancellor for Research,Tabriz
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 90
Inclusion Criteria
Pregnant women at high risk for the possibility of preeclampsia
Consent to participate in the study
Pregnancy age 16 to 20 weeks
Having minimum literacy
Having a phone number to follow up
History of preeclampsia in previous pregnancy
In Vitro Fertilization (IVF)
Family history of preeclampsia
BMI 35 and above
Age over 40 years
Exclusion Criteria
Uso de anticoagulantes, excepto aspirina.
History of allergy to statins
Multiple pregnancy
History of thrombophilia
Chronic kidney disease
Autoimmune disease
Cardiovascular diseases
Smoking and alcohol consumption
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Preeclampsia. Timepoint: before the intervention (16 weeks of pregnancy), then in the second visit (20 weeks of pregnancy), the third visit (24 weeks of pregnancy), the fourth visit (28 weeks of pregnancy), the fifth visit (30 weeks of pregnancy), sixth visit 32th week of pregnancy), seventh visit (34 th week of pregnancy) and eighth visit (38-40 th week of pregnancy). Method of measurement: mercury sphygmomanometer with a suitable cuff from the right arm in a sitting position after 15 The minute of rest.
- Secondary Outcome Measures
Name Time Method