Atorvastatin in acute intracerebral hemorrhage.
Phase 3
Recruiting
- Conditions
- Intracerebral Hemorrhage.Nontraumatic intracerebral hemorrhage in hemisphere, unspecifiedI61.2
- Registration Number
- IRCT20141116019971N6
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 92
Inclusion Criteria
Age < 80 years.
Intracerebral hemorrhage confirmed by ?rain CT scan without contrast.
low-density lipoprotein (LDL) level >40 mg/dL.
Exclusion Criteria
Pregnancy.
Coma at the time of admission.
History of neurodegenerative disorders such as Alzheimer's disease, Multiple sclerosis, Parkinson's disease, previous stroke, and psychological problems.
History of brain tumors.
Intracerebral hemorrhage due to vascular malformation or coagulation disorders.
Intracerebral hemorrhage which requires surgical evacuation.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum level of Matrix metallopeptidase 9. Timepoint: At the time of admission (before intervention) and after 14 and 45 days of Atorvastatin consumption. Method of measurement: Blood Sample.;Serum level of Vascular endothelial growth factor. Timepoint: At the time of admission (before intervention) and after 14 and 45 days of Atorvastatin consumption. Method of measurement: Blood Sample.
- Secondary Outcome Measures
Name Time Method