Open Lung Approach Versus Standard Protective Strategies
Not Applicable
Completed
- Conditions
- Lung Collapse
- Registration Number
- NCT02798133
- Lead Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
- Brief Summary
The aim of this study was to compare the effects of adding a recruitment maneuver (RM) to low tidal volume (VT) ventilation, with or without an individualized post-RM positive end-expiratory pressure (PEEP) setting in lung-healthy patients during anesthesia.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 36
Inclusion Criteria
- ASA physical status I-III undergoing elective major abdominal surgery including pancreatic-duodenectomy, gastrectomy and liver resection
Exclusion Criteria
- i) laparoscopic surgery, ii) patients with previous respiratory disease.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method driving pressure intraoperative The driving pressure is a physiological ventilatory parameter measured as platteau pressure minus PEEP. This parameter may be associated with postoperative pulmonary complications
- Secondary Outcome Measures
Name Time Method ventilatory efficiency intraoperative Ventilatory efficiency measured with volumetric capnography which includes dead space and tidal elimination of carbon dioxide.