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临床试验/NCT05613855
NCT05613855尚未招募不适用

Performance of Pulmonary Embolism Risk Scores for Assessment of Outcome in Computed Tomographic Pulmonary Angiography Confirmed Patients

Assiut University0 个研究点目标入组 60 人开始时间: 2022年11月最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
60
主要终点
Assess performance of PERFORM score in predicting outcome in CTPA confirmed patients.

研究概览

简要总结

  1. Assess performance of PERFORM score in predicting outcome in CTPA confirmed patients.
  2. Compare PERFORM score with the currently validated PESI in risk stratification of patients

详细描述

Pulmonary embolism (PE) is a common and potentially lethal condition in the emergency department requiring early and accurate management.

The short-term mortality rate of PE varies widely and ranges from less than 2% in many patients with non massive PE to more than 95% in patients who experience cardiorespiratory arrest.

Although several prognostic models of acute PE are currently used, all of them have practical limitations.

Of all clinical scores integrating PE severity and comorbidity, the Pulmonary Embolism Severity Index (PESI) and its simplified version,(sPESI) have been most extensively validated to date.

However, current prognostic scores for pulmonary embolism (PE) are partly based on patients without PE confirmation via computed tomographic pulmonary angiography (CTPA), involving subjective parameters and complicated scoring methods [8].

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients above 18 years old with PE confirmed by CTPA are considered for inclusion in the study.

排除标准

  • • Patients who have contraindications for CTPA eg. Renal impairment
  • Patients diagnosed and treated as PE without doing CTPA.
  • Patients who refuse to participate in the study

结局指标

主要结局

Assess performance of PERFORM score in predicting outcome in CTPA confirmed patients.

时间窗: from 11/2022 to 4/2024

次要结局

  • Compare PERFORM score with the currently validated PESI in risk stratification of patients.(from 11/2022 to 4/2024)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Nourhan Safwat Abdelraheem Hussien

Resident doctor

Assiut University

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