Prognostic Factors for Acute Pulmonary Embolism in Critically Ill Patients

Completed

• Conditions: Acute Pulmonary Embolism (PE)

• Registration Number: NCT01839266
• Lead Sponsor: Yonsei University

Brief Summary

Acute pulmonary embolism (PE) is an important cause of in-hospital mortality and may be rapidly fatal if not diagnosed and treated. Despite recent advances in diagnostic and therapeutic modalities, it is still one of the important causes of hospital mortality. Previous several reports have described the variable outcome of patients with PE with reported mortality rate ranging from 8.1% (stable patients) to 25% (with cardiogenic shock) and 65% (post cardiopulmonary resuscitation). Nevertheless, there are no published studies from Korean hospitals that assessed the outcome of acute PE treated in the hospital with IV unfractionated heparin. We conducted this study to determine the outcome, risk factors, clinical characteristics and demographics of patients with acute PE and to identify possible demographic and clinical factors associated with prognosis.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2011-11
• Primary Completion: 2012-12
• Status Verified: 2013-04
• Study Completion: 2013-04
• Study First Submitted: 2013-04-01
• Study First Submitted QC: 2013-04-21
• Last Update Submitted: 2013-04-21
• Study First Posted: 2013-04-24
• Last Update Posted: 2013-04-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

patients admitted to the Severance Hospital, Yonsei University Health System with primary diagnosis of PE between January 2008 and December 2012. (diagnosed by CT and treated in the hospital with IV unfractionated heparin)

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Exclusion Criteria

1. diagnosis was prior to arrivalor
2. anticoagulation was contraindicated
3. diagnosis was not confirmed by CT

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
prognostic factors of overall survival	change of acute pulmonary embolism(PE) for duration of hospital stay an expected average of 12 months	In-hospital all-cause mortality with acute pulmonary embolism(PE) treated in the hospital with IV unfractionated heparin

Trial Locations

Locations (1)

Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Chief of ICUs, Severance Hospital, Yonsei University Health System; 🇰🇷 Seoul, Korea, Republic of