Prognostic Factors for Acute Pulmonary Embolism in Critically Ill Patients
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Yonsei University
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- prognostic factors of overall survival
Study Overview
Brief Summary
Acute pulmonary embolism (PE) is an important cause of in-hospital mortality and may be rapidly fatal if not diagnosed and treated. Despite recent advances in diagnostic and therapeutic modalities, it is still one of the important causes of hospital mortality. Previous several reports have described the variable outcome of patients with PE with reported mortality rate ranging from 8.1% (stable patients) to 25% (with cardiogenic shock) and 65% (post cardiopulmonary resuscitation). Nevertheless, there are no published studies from Korean hospitals that assessed the outcome of acute PE treated in the hospital with IV unfractionated heparin. We conducted this study to determine the outcome, risk factors, clinical characteristics and demographics of patients with acute PE and to identify possible demographic and clinical factors associated with prognosis.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 34 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •patients admitted to the Severance Hospital, Yonsei University Health System with primary diagnosis of PE between January 2008 and December
- •(diagnosed by CT and treated in the hospital with IV unfractionated heparin)
Exclusion Criteria
- •diagnosis was prior to arrivalor
- •anticoagulation was contraindicated
- •diagnosis was not confirmed by CT
Outcomes
Primary Outcomes
prognostic factors of overall survival
Time Frame: change of acute pulmonary embolism(PE) for duration of hospital stay an expected average of 12 months
In-hospital all-cause mortality with acute pulmonary embolism(PE) treated in the hospital with IV unfractionated heparin
Secondary Outcomes
No secondary outcomes reported