Contemporary Clinical Management Of Acute Pulmonary Embolism. The COPE Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acute Pulmonary Embolism
- Sponsor
- Heart Care Foundation
- Enrollment
- 5213
- Locations
- 181
- Primary Endpoint
- In-hospital death
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
Acute pulmonary embolism is a potentially life-threatening disease with short-term mortality ranges from less than 1% to more than 30% during the hospital stay. Recent guidelines recommend to tailor diagnosis hospitalization and acute treatment based on the estimated risk for short-term Death.
The assessment of the contemporary clinical management of patients with acute pulmonary embolism across different specialties would be of crucial value.
Detailed Description
This is a prospective, non-interventional, multicenter study in patients with acute pulmonary embolism admitted to Cardiology, Emergency and Internal Medicine Departments in Italy. The aim of the study is to assess contemporary management strategies in patients with acute pulmonary embolism in terms of diagnosis, risk stratification, hospitalization and treatment in Italy and assess 1. their association with in-hospital and 30-day mortality and 2. their adherence to current guidelines of the European Society of Cardiology (ESC).
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients with acute, symptomatic acute pulmonary embolism
- •Age ≥ 18 years
- •Informed consent
Exclusion Criteria
- •refusal of informed consent
- •participation in controlled trials on the management of patients with acute pulmonary embolism
Outcomes
Primary Outcomes
In-hospital death
Time Frame: 30 days
In-hospital Death and Death at 30 days
Secondary Outcomes
- All cause Mortality and clinical worsening(30 days)
- Pulmonary embolism related mortality for and clinical worsening(30 days)
- Adherence to guidelines(30 days)