Contemporary Clinical Management Of Acute Pulmonary Embolism. The COPE Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 5,213
- 试验地点
- 181
- 主要终点
- In-hospital death
研究概览
简要总结
Acute pulmonary embolism is a potentially life-threatening disease with short-term mortality ranges from less than 1% to more than 30% during the hospital stay. Recent guidelines recommend to tailor diagnosis hospitalization and acute treatment based on the estimated risk for short-term Death.
The assessment of the contemporary clinical management of patients with acute pulmonary embolism across different specialties would be of crucial value.
详细描述
This is a prospective, non-interventional, multicenter study in patients with acute pulmonary embolism admitted to Cardiology, Emergency and Internal Medicine Departments in Italy.
The aim of the study is to assess contemporary management strategies in patients with acute pulmonary embolism in terms of diagnosis, risk stratification, hospitalization and treatment in Italy and assess
- their association with in-hospital and 30-day mortality and
- their adherence to current guidelines of the European Society of Cardiology (ESC).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with acute, symptomatic acute pulmonary embolism
- •Age ≥ 18 years
- •Informed consent
排除标准
- •refusal of informed consent
- •participation in controlled trials on the management of patients with acute pulmonary embolism
结局指标
主要结局
In-hospital death
时间窗: 30 days
In-hospital Death and Death at 30 days
次要结局
- All cause Mortality and clinical worsening(30 days)
- Pulmonary embolism related mortality for and clinical worsening(30 days)
- Adherence to guidelines(30 days)