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A Two Arm, Multi-Site Clinical Evaluation of the ARIES HSV 1&2 Assay in Symptomatic Patients

Completed
Conditions
Herpes
Registration Number
NCT02092233
Lead Sponsor
Luminex Corporation
Brief Summary

The ARIES HSV 1\&2 Assay is a PCR based test for the direct detection and typing of herpes simplex virus (HSV 1 \& 2) DNA.

The objective is to establish the diagnostic accuracy of ARIES HSV-1\&2 Assay.

Detailed Description

The ARIES HSV 1\&2 Assay is a polymerase chain reaction (PCR) based qualitative in vitro diagnostic test for the direct detection and typing of herpes simplex virus (HSV 1 \& 2) DNA in male external and internal anogenital, female external and internal anogenital (vaginal), oral and skin lesion specimens.

The objective is to establish the diagnostic accuracy of ARIES HSV-1\&2 Assay through a multi-site, method comparison on prospectively collected, left-over de-identified, clinical specimens (i.e. all-comers accrued at enrolled clinical sites between pre-determined dates) as an aid in the diagnosis of herpes infection.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1963
Inclusion Criteria

The specimen is from one of the following lesion sources: male internal and external anogenital, female internal anogenital, female external anogenital, oral or skin The specimen is collected and maintained in unexpired Copan universal transport medium

Exclusion Criteria

The specimen was not properly collected, transported or stored according to instructions provided by Sponsor

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Diagnostic accuracy will be expressed in terms of clinical sensitivity (or positive agreement) and specificity (or negative agreement).Within the first year of sample collection
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (3)

Baystate Medical Center

🇺🇸

Springfield, Massachusetts, United States

Tricore

🇺🇸

Albuquerque, New Mexico, United States

Labcorp

🇺🇸

Burlington, North Carolina, United States

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