ong-term Outcome of Hospitalized Patients with Acute Severe Ulcerative Colitis Treated with Infliximab: Multicenter Retrospective Cohort Study in Korea)
Not Applicable
Recruiting
- Conditions
- Diseases of the digestive system
- Registration Number
- KCT0002799
- Lead Sponsor
- Kyung Hee University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Male
- Target Recruitment
- 500
Inclusion Criteria
Patients who were hospiatlized for acute severe UC and satisfying Truelove and Witts criteria for severe colitis; = 6 bloody stools per day and one or more of the following: decreased hemoglobin (<10.5 g/dL), elevated ESR (>30 mm/h), fever (>37.8?), or tachycardia (>90 bpm)
Exclusion Criteria
?Patients who were not treated with steroid or anti-TNF agents.
?Patients diagnosed with an unclassified-IBD
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Colectomy;Rehospitalization due to aggravation or complication of disease;Rate of death
- Secondary Outcome Measures
Name Time Method Predictive factors for initial treatment failure, colectomy, rehospitalizaion and death;Investigate the annual trends in prevalence of CMV colitis and the effect of antiviral treatment and characteristics of recurrent CMV colitis in patients with ASUC;Trend analysis of standard hospitalization, rehospitazliation, colectomy, and death due to acute severe ulcerative colitis