The use of stem cells for the treatment of the cartilage lesions
Not Applicable
Recruiting
- Conditions
- Destructive lesions of the knee joint cartilage.Disorder of cartilage, unspecified
- Registration Number
- IRCT2017052634053N2
- Lead Sponsor
- Hamadan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 16
Inclusion Criteria
aged between 15 years to 40 years; the lesion between 2.5 and 6 square centimeters; the lesions of trauma sports and non-sports injury; femoral condyle internal or external lesions Exclusion criteria: Obesity; corticosteroid injection less than 3 months ago; hyaluronic acid injection less than 6 months ago; varus and valgus more than 5 degree; diabetes type one and two; autoimmune disease; malnutrition; certain neurological diseases; history of allergy; infectious diseases
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Articular cartilage lesions of the knee. Timepoint: 3.6.12,18 weeks. Method of measurement: MRI and diagnostic arthroscopy.
- Secondary Outcome Measures
Name Time Method Glycosaminoglycans, collagen, gene and protein expression of, agercan, collagen type II and sox9. Timepoint: Eighteenth week. Method of measurement: biochemical, molecular and immunocytochemistry analysis.