MedPath

Virtual Peer-to-peer Support Programme for Carers of MND

Not Applicable
Recruiting
Conditions
Amyotrophic Lateral Sclerosis
Motor Neuron Disease
Interventions
Behavioral: Virtual peer-to-peer support
Registration Number
NCT04695210
Lead Sponsor
King's College London
Brief Summary

Background/scope There is growing recognition that family caregiving is a serious public health issue requiring supportive interventions. Family caregivers play an essential role in sustaining a stable environment enabling individuals with motor neurone disease (MND) that are technology dependent to live at home. The family caregivers can experi¬ence exceptional burden and significant decline in psychological wellbeing due to MND's rapid and pro¬gressive nature with profoundly debilitating effects and intensive support needs. Dependence on assistive technology adds an additional level of complexity to family caregiving due to the need to learn how to operate and troubleshoot medical devices, train other caregivers, and negotiate appointments with new specialties within the healthcare system.

Despite the recognized impact of caregiving for individuals with MND, data are scarce as to effective interventions that provide direct practical and psychosocial supports. Difficulty accessing support may increase psychological distress. As the burden of caring increases due to disease progression and increasing technology dependence, access to existing informal support networks may diminish. Online peer support using virtual modalities is a flexible and low cost form of support. Peers, people who have experienced the same health problem and have similar characteristics as support recipients, can be a key source of emotional, informational, and affirmational support. Peer support improves psychological well-being of caregivers of people with conditions such as dementia, cancer, and brain injury. Although peer support programmes for family caregivers of people with MND exist, data as to their efficacy are limited. Therefore, we have developed an online peer support programme, completed beta and usability testing and now propose to test the effect on caregiver psychological wellbeing and caregiver burden.

Aim/research question(s) Overall aim: to determine the efficacy of a 12-week online peer support programme on family caregiver psychological health and caregiver burden.

Primary research question:

What is the effect of the online peer support programme on psychological distress measured using the Hospital Anxiety and Depression Scale (HADS)?

Secondary research questions:

1. What is the effect on positive affect, caregiver burden, caregiving mastery, caregiving personal gain, and coping?

2. How do participants use the programme (fidelity and reach)?

3. What is the perceived usability and acceptability?

Methods The investigators will conduct a parallel group randomised controlled trial with participants allocated to 12-week access to the online peer support programme or a usual care control group. The investigators will enrol family caregivers of an individual with MND who is referred for consideration or receiving any of the following

1. assisted ventilation

2. cough assist

3. gastroscopy and enteral feeding

i.e., entering King's clinical staging Stage 4A: nutritional support; or Stage 4B: respiratory support \[51\]:

The 12-week peer-to-peer support programme entails:

1. audio, video, or text private messaging;

2. synchronous weekly chat;

3. asynchronous discussion forum; and

4. informational resources.

The investigators will collect demographic and caregiving data including the Caregiver Assistance Scale and Caregiving Impact Scale, and caregiver measures (HADS, Positive and Negative Affect Schedule, Zarit Burden Interview, Pearlin Mastery Scale, Personal Gain Scale, Brief COPE) at baseline and programme completion.

The investigators will download use of online peer support programme features, assess usability, and conduct semi-structured interviews to explore acceptability using the Theoretical Framework of Acceptability.

To test for a medium size effect (d=0.5), at 5% level of significance (2-sided) with power 80%, 64 participants are required in each arm (128 total). Adjusting for 20% attrition requires 154 participants.

Proposed findings The proposed study will demonstrate the effect of a online peer support programme on psychological distress, positive affect, caregiving burden, mastery, personal gain and coping. Data on programme fidelity will enable the investigators to objectively assess acceptability and interpret study results. Data on usability and acceptability will inform future scalability of the online peer support programme outside of the trial both nationally and internationally, and to other family caregiver populations.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
154
Inclusion Criteria
  1. age ≥ 18 years;

  2. family/informal caregiver of an individual with MND living at home who is referred for consideration or receiving any of the following i.e., entering King's clinical staging Stage 4A: nutritional support; or Stage 4B: respiratory support [51]:

    1. assisted ventilation
    2. cough assist
    3. gastroscopy and enteral feeding
  3. able to speak/read English;

  4. has access to a computer, tablet, or smartphone and the internet (we have the ability to provide loan 4G enabled tablets if required); and

  5. consents to participation

Exclusion Criteria
  1. Actively receiving psychiatric/psychologist care identified through self-report.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Virtual Peer-to-Peer SupportVirtual peer-to-peer supportThose participants randomised to the intervention arm will have access to a 12-week virtual peer-to-peer support programme which entails: 1. weekly audio, video, or text private messaging with a peer supporter; 2. synchronous weekly discussion forum attended by peer supporters and family caregiver participants moderated by the research team. These forums will discuss specific topics (e.g. caregiver self-care, the emotional impact of caregiving). Ask the expert forums will be moderated by clinical experts every 6 weeks (meaning all participants will have access to 2 ask the expert sessions); 3. asynchronous discussion forums in which participants can post questions; and 4. access to informational resources.
Primary Outcome Measures
NameTimeMethod
Hospital Anxiety and Depression Score (HADS)6 weeks & 12 weeks

Change in Hospital Anxiety and Depression Score from baseline to programme completion. The Hospital Anxiety and Depression Score Overall score ranges from 0 \[best\] to 21 \[worst\] with cutoff points of \>7 (possible) and \>10 (probable) indicating cases of anxiety or depression.

Secondary Outcome Measures
NameTimeMethod
Zarit Burden Interview (ZBI)6 weeks & 12 weeks

Change in ZBI score from baseline to programme completion. The sum of scores ranges between 0 to 88. Higher scores indicate greater burden. Caregivers can be categorised as 'highly burdened' (score of ≥ 24) and low burdened groups (score \<24)

Positive and Negative Affect Schedule12 weeks

10-item Positive Affect Scale of the Positive and Negative Affect Schedule from baseline to programme completion. Scores range from 10 to 50; higher scores indicate more psychological well-being.

Brief-COPE (note COPE is not an abbreviation)12 weeks

Change in Brief COPE from baseline to programme completion. 14 scales with 2 items (28 items in total. Scores on each scale range from 2 (minimum) to 8 (maximum). Higher scores indicate increased utilisation of that specific coping strategy.

Pearlin Mastery Scale12 weeks

Change in Pearlin Mastery Scale from baseline to programme completion. The Pearlin Mastery Scale is a 7 item scale with scores from 7 to 28. Higher scores indicate a greater sense of control over life.

Trial Locations

Locations (25)

Bedfordshire Hospitals NHS Foundation Trust

🇬🇧

Bedford, United Kingdom

Airedale NHS Foundation Trust

🇬🇧

Bradford, United Kingdom

University Hospitals Sussex NHS Foundation Trust

🇬🇧

Brighton, United Kingdom

Pilgrims Hospice

🇬🇧

Canterbury, United Kingdom

Coventry Community Specialist Palliative Care Team

🇬🇧

Coventry, United Kingdom

University Hospitals Coventry and Warwickshire NHS Trust

🇬🇧

Coventry, United Kingdom

Ninewells Hospital

🇬🇧

Dundee, United Kingdom

Royal Devon University Healthcare NHS Foundation Trust

🇬🇧

Exeter, United Kingdom

Phyllis Tuckwell Hospice

🇬🇧

Farnham, United Kingdom

Medway Community Healthcare

🇬🇧

Gillingham, United Kingdom

Kingston Hospital NHS Foundation

🇬🇧

Kingston upon Thames, United Kingdom

The Leicestershire & Rutland Organisation for the Relief of Suffering - LOROS

🇬🇧

Leicester, United Kingdom

The Walton Centre NHS Foundation Trust

🇬🇧

Liverpool, United Kingdom

Guy's and St Thomas' NHS Foundation Trust

🇬🇧

London, United Kingdom

Lancashire Teaching Hospitals NHS Foundation Trust

🇬🇧

Many Locations, United Kingdom

Marie Curie Hospice

🇬🇧

Many Locations, United Kingdom

Nottinghamshire Healthcare NHS Foundation Trust

🇬🇧

Many Locations, United Kingdom

Swansea Bay University Health Board

🇬🇧

Many Locations, United Kingdom

Royal Stoke University Hospital/University Hospitals North

🇬🇧

Multiple Locations, United Kingdom

University Hospitals Plymouth NHS trust

🇬🇧

Plymouth, United Kingdom

Sheffield Teaching Hospitals NHS Foundation Trust

🇬🇧

Sheffield, United Kingdom

Severn Hospice

🇬🇧

Shrewsbury, United Kingdom

St Margaret's Hospice

🇬🇧

Taunton, United Kingdom

Hounslow and Richmond Community Healthcare

🇬🇧

Teddington, United Kingdom

Compton Care

🇬🇧

Wolverhampton, United Kingdom

© Copyright 2025. All Rights Reserved by MedPath