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Role of granulocyte colony stimulating factor or human chorionic gonadotropin in improving embryo implantatio

Not Applicable
Conditions
Fertility-female
Registration Number
PACTR202006915851110
Lead Sponsor
Wald we bent center
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
Female
Target Recruitment
150
Inclusion Criteria

women aged 20-43 years old undergoing ICSI cycles
history of recurrent implantation failure at least 1 cycle in which she had day 5 embryo transfer

Exclusion Criteria

Women with renal sickle cell disease
history of malignancy
history of poor quality embryos
risk of Ovarian hyperstimulation syndrome (OHSS)

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
clinical pregnancy rate (defined as viable pregnancy when there is evidence of gestational sac, embryo and fetal heart activity at time of trans-vaginal ultrasound evaluation by the 8th week) ;implantation rate (defined as the number of gestational sacs observed at echographic screening at 6 weeks of pregnancy divided by the number of embryos transferred).
Secondary Outcome Measures
NameTimeMethod
Biochemical pregnancy rate (defined as positive from quantative values of serum test of ß-hCG according to the standard values used in the laboratory at second week) ;miscarriage rate (defined as the loss of pregnancy before 8th weeks‘ gestational age
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