Effect of human chorionic gonadotropin and embryo glue in infertility
Phase 3
- Conditions
- Infertility.Complications associated with artificial fertilization
- Registration Number
- IRCT20221126056614N1
- Lead Sponsor
- Mazandaran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 158
Inclusion Criteria
Women who have a history of at least 3 failed transfer cycles or failed transfer of 4 good quality (grade A or B) embryos.
Women who are in the frozen-thawed embryo transfer cycle and their preparation is done using estrogen and progesterone.
Women who have at least one grade A or B embryo on the day of embryo transfer
Exclusion Criteria
Donated oocyte
Donated embryo
Surrogacy
Presence of hydrosalpinx in hysterosalpingography or ultrasound
History of uncontrolled endocrine diseases: diabetes, hypothyroidism and hyperthyroidism
Male factor infertility (azoospermia)
Difficult embryo transfer (needs manipulation of the cervix or under anesthesia)
Uterine abnormalities
Presence of severe endometriosis and endometrioma
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Rate of Implantation. Timepoint: 5 weeks after intervention. Method of measurement: Ultrasound.;Rate of Abortion. Timepoint: 18 weeks after intervention. Method of measurement: Fetus excretion.;Rate of chemical pregnancy. Timepoint: 3-4 weeks after intervention. Method of measurement: Pregnancy test.;Rate of clinical pregnancy. Timepoint: 5 weeks after intervention. Method of measurement: Ultrasound.;Ongoing pregnancy. Timepoint: 38 weeks after intervention. Method of measurement: Delivery.
- Secondary Outcome Measures
Name Time Method