Development of Protocols and Methods for Image Processing and Enhancement of MRI Data
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- MRI Image Enhancement
- Sponsor
- Hillel Yaffe Medical Center
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Diagnostic quality
- Last Updated
- 4 years ago
Overview
Brief Summary
The purpose of the study is to develop new Magnetic Resonance Imaging (MRI) protocols and methods for image processing and enhancement. Different setting of acquisition parameters used in conventional clinical MRI protocols will be defined, to create "New Protocols". Then post-processing will be applied on new protocols to enhance the image quality. Finally a comparison of image quality will be performed to compare the image quality of images obtained by conventional protocols with those obtained with the New Protocols.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Volunteers for clinical MRI examination
- •Patients undergoing clinical MRI examination
- •Capable to provide an informed written consent form
Exclusion Criteria
- •Any contraindication to MRI scanning, such as pacemakers or heart rhythm disturbances, permanent cosmetics or certain metallic implants in the body (excluding dental implants).
- •Age \<18 years old
- •Pregnancy
- •Claustrophobia
Outcomes
Primary Outcomes
Diagnostic quality
Time Frame: Through study completion, an average of 2 months.
Comparing diagnostic quality of images obtained by conventional protocols with the corresponding New Protocols' processed images. The comparison will be performed by neuroradiologists, using a 7-point Likert-scale. Where higher the score, better the outcome (1 means unacceptable and 7 means excellent).
Image Resolution
Time Frame: Through study completion, an average of 2 months.
Comparing the resolution of images obtained by conventional protocols with the corresponding New Protocols' processed images. The comparison will be performed by neuroradiologists, using a 7-point Likert-scale. Where higher the score, better the outcome (1 means unacceptable and 7 means excellent).
Artifacts
Time Frame: Through study completion, an average of 2 months.
Comparing artifacts of images obtained by conventional protocols with the corresponding New Protocols' processed images. The comparison will be performed by neuroradiologists, using a 7-point Likert-scale. Where higher the score, better the outcome (1 means unacceptable and 7 means excellent).
MRI contrast
Time Frame: Through study completion, an average of 2 months.
Comparing MR contrast of images obtained by conventional protocols with the corresponding New Protocols' processed images. The comparison will be performed by neuroradiologists, using a 7-point Likert-scale. Where higher the score, better the outcome (1 means unacceptable and 7 means excellent).
Image Signal to Noise Ratio (SNR)
Time Frame: Through study completion, an average of 2 months.
Comparing the SNR of images obtained by conventional protocols with the corresponding New Protocols' processed images. The comparison will be performed by neuroradiologists, using a 7-point Likert-scale. Where higher the score, better the outcome (1 means unacceptable and 7 means excellent).