Development of Protocols and Methods for Image Processing and Enhancement of MRI Data

• Conditions: MRI Image Enhancement

• Registration Number: NCT04861532
• Lead Sponsor: Hillel Yaffe Medical Center

Brief Summary

The purpose of the study is to develop new Magnetic Resonance Imaging (MRI) protocols and methods for image processing and enhancement. Different setting of acquisition parameters used in conventional clinical MRI protocols will be defined, to create "New Protocols". Then post-processing will be applied on new protocols to enhance the image quality. Finally a comparison of image quality will be performed to compare the image quality of images obtained by conventional protocols with those obtained with the New Protocols.

Detailed Description

Not available

Study Timeline

• Status Verified: 2021-04
• Study Start: 2021-04-01
• Study First Submitted: 2021-04-14
• Study First Submitted QC: 2021-04-22
• Study First Posted: 2021-04-27
• Last Update Submitted: 2021-06-07
• Last Update Posted: 2021-06-10
• Primary Completion: 2021-09-01
• Study Completion: 2021-12-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Volunteers for clinical MRI examination
• Patients undergoing clinical MRI examination
• Capable to provide an informed written consent form

Exclusion Criteria

• Any contraindication to MRI scanning, such as pacemakers or heart rhythm disturbances, permanent cosmetics or certain metallic implants in the body (excluding dental implants).
• Age <18 years old
• Pregnancy
• Claustrophobia

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Diagnostic quality	Through study completion, an average of 2 months.	Comparing diagnostic quality of images obtained by conventional protocols with the corresponding New Protocols' processed images. The comparison will be performed by neuroradiologists, using a 7-point Likert-scale. Where higher the score, better the outcome (1 means unacceptable and 7 means excellent).
Image Resolution	Through study completion, an average of 2 months.	Comparing the resolution of images obtained by conventional protocols with the corresponding New Protocols' processed images. The comparison will be performed by neuroradiologists, using a 7-point Likert-scale. Where higher the score, better the outcome (1 means unacceptable and 7 means excellent).
Artifacts	Through study completion, an average of 2 months.	Comparing artifacts of images obtained by conventional protocols with the corresponding New Protocols' processed images. The comparison will be performed by neuroradiologists, using a 7-point Likert-scale. Where higher the score, better the outcome (1 means unacceptable and 7 means excellent).
MRI contrast	Through study completion, an average of 2 months.	Comparing MR contrast of images obtained by conventional protocols with the corresponding New Protocols' processed images. The comparison will be performed by neuroradiologists, using a 7-point Likert-scale. Where higher the score, better the outcome (1 means unacceptable and 7 means excellent).
Image Signal to Noise Ratio (SNR)	Through study completion, an average of 2 months.	Comparing the SNR of images obtained by conventional protocols with the corresponding New Protocols' processed images. The comparison will be performed by neuroradiologists, using a 7-point Likert-scale. Where higher the score, better the outcome (1 means unacceptable and 7 means excellent).

Trial Locations

Locations (1)

Hillel Yaffe; 🇮🇱 Hadera, Select One, Israel