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Clinical Trials/DRKS00026025
DRKS00026025Recruiting未知

Follow-up study to evaluate the role of circulating cell-derived extracellular vesicles (EVs) in polytrauma

Bundeswehrzentralkrankenhaus Koblenz0 sites80 target enrollmentStarted: August 11, 2021Last updated:
Conditions

Trial Snapshot

Phase
未知
Status
Recruiting
Enrollment
80

Study Overview

Brief Summary

No summary available.

Study Design

Study Type
Interventional
Allocation
Randomized controlled study
Masking
Blinded (masking used)

Eligibility Criteria

Ages
18 Years to one (—)
Sex
All

Inclusion Criteria

  • Trauma patient with ISS >9

Exclusion Criteria

  • No declaration of consent, pregnancy, participants unter 18 years old, doubts about the patient's ability to consent or signs of dementia, as well as incomplete blood collection series. In addition, patients with acute or chronic inflammation, e.g., autoimmune hepatitis, but also genetic diseases, cholestatic diseases, and patients with co-infection, such as HCV and HBV or HCV and HIV, are excluded, as these have been shown to alter the fibrolytic EV profile.

Investigators

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