Actively working on recovery: The influence of physical activity on PTSD treatment outcome.

Completed

Conditions: 'Post-traumatic stress disorder' and 'Stress disorder'
10002861

Registration Number: NL-OMON49822

Lead Sponsor: PSYTREC

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 120

Inclusion Criteria

In order to be eligible to participate in this study, subjects must meet all of
the following criteria: (1) a diagnosis of PTSD based on the
Clinician-Administered PTSD Scale (CAPS-5), (2) being at least 18 years old (3)
sufficient knowledge of the Dutch language to undergo treatment.

Exclusion Criteria

Potential subjects who meet any of the following criteria will be excluded from
participation in this study: (1) a suicide attempt less than three months prior
to treatment, (2) being medically unfit to participate in the physical activity
intervention operationalized as not being able to walk for at least 30 minutes
(e.g., physical impairments that necessitate the use of wheelchair).

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcome measure is the change in PTSD symptoms from pre- to<br /><br>posttreatment and at 6-month follow-up, measured with the<br /><br>Clinician-Administered PTSD Scale (CAPS-5) and the PTSD Checklist for DSM-5<br /><br>(PCL-5).</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secondary outcome measures are the underlying biological and psychological<br /><br>mediators, measured with the Cortisol Awakening Response (CAR), inflammation<br /><br>levels, DNA methylation, Insomnia Severity Index (ISI), Depressive<br /><br>Symptomatology Self-Report (QIDS-SR), Difficulties in Emotion Regulation Scale<br /><br>(DERS), Dissociative Experiences Scale-II (DES-II), and the Anxiety Sensitivity<br /><br>Index (ASI).</p><br>