Evaluation and Co-relation of vitamin D levels and jaw bone mineral density in premenopausal and postmenopausal female patients undergoing implant therapy. An In-vivo Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- There will be the significant co-relation between Vitamin d and jaw bone mineral density in menopausal condition
研究概览
简要总结
This Study aims toEvaluate and co-relate Vitamin D levels and Jaw Bone mineral density in pre andpostmenopausal females undergoing implant therapy. Vitamin D is a vitamin as well as a hormone thatour bodies produce. It is a fat-soluble vitamin that has long been known to aidin the absorption and retention of calcium and phosphorus, both of which areessential for bone formation. The correlation of vitamin D level and menopausalcondition on jaw bone in relation to its bone mineral density for dentalimplant therapy have not been well documented, therefore this study is plannedto be carried out.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- Female
入选标准
- •All premenopausal and Postmenopausal females [18 years to 70 years] either edentulous or partially edentulous and willing to participate in the study.
- •No history of oophorectomy or hysterectomy For the test group subjects with history of vitamin D deficiency were chosen after confirmation with their medical records and cross-checking values of serum Vitamin D level (ng/ml).
- •Patient having unfavorable condition location and number of abutment teeth.
- •The patient should not have any medical conditions (besides osteoporosis) that would make implant treatment more complicated.
- •They should have no local disease or condition that could interfere with implant treatment such as periodontal disease endodontic problems caries occlusal problems tooth fracture tooth wear and bony lesions .
排除标准
- •Hyperparathyroidism, renal dystrophy, oophorectomy, and skeletal bone disorders significantly affect bone metabolism.
- •As well as the usage of bone-related medications such as corticosteroids, estrogens preparations, bisphosphonates, and vitamin D supplements.
- •Uncontrolled diabetes, Uncontrolled hypothyroidism, habit of Smoking, Alcoholics Pregnancy Psychological instability Cancer radiation and chemotherapy History of radiation therapy to the jaws Habit of bruxism Bad oral hygiene which continues despite of motivating treatment.
结局指标
主要结局
There will be the significant co-relation between Vitamin d and jaw bone mineral density in menopausal condition
时间窗: Assessment will be done at the end of the study. Total duration of study is 18 months .
次要结局
- the reduction in jaw Bone mineral density related to vitamin D deficiency in postmenopausal female patients undergoing implant therapy(Assessment at the end of the study .Total duration of the study will be at 12 months & 18 months)